TY - JOUR
T1 - Treatment of superficial carcinoma in hypopharynx
AU - Satou, Yasuo
AU - Omori, Tai
AU - Tagawa, Munemasa
PY - 2006
Y1 - 2006
N2 - Superficial carcinoma of the esophagus is generally treated with endoscopic mucosal resection (EMR), yielding an acceptable prognosis and quality of life (QOL). With technical advances in endoscopy, it has become to possible to find superficial carcinoma even in the hypopharynx. Several reports suggest that such superficial carcinomas are treatable only with local mucosal resection. We treated 67 superficial carcinomas (49 cases) of the hypopharynx with local mucosal resection in our hospital, mainly with EMR. From 2004, we have resected 11 lesions directly with endoscopic assist (endoscopic laryngopharyngeal surgery; ELPS). With ELPS, it was very easy to recognize lugol-voiding lesions in the hypopharynx, and ELPS enabled us to do en bloc resection even for large lesions that could not be treated with EMR or with microscopic surgery. Eight of 49 cases had transient side effects-2 vocal cord palsies, 2 vocal cord edemas with overnight intubation, 3 overnight intubations, and 1 pharyngitis. Six patients died of other diseases, and no metastasis or recurrence of superficial carcinoma was found. Diagnosis and treatment of superficial carcinoma of the hypopharynx may thus improve patient prognosis and QOL.
AB - Superficial carcinoma of the esophagus is generally treated with endoscopic mucosal resection (EMR), yielding an acceptable prognosis and quality of life (QOL). With technical advances in endoscopy, it has become to possible to find superficial carcinoma even in the hypopharynx. Several reports suggest that such superficial carcinomas are treatable only with local mucosal resection. We treated 67 superficial carcinomas (49 cases) of the hypopharynx with local mucosal resection in our hospital, mainly with EMR. From 2004, we have resected 11 lesions directly with endoscopic assist (endoscopic laryngopharyngeal surgery; ELPS). With ELPS, it was very easy to recognize lugol-voiding lesions in the hypopharynx, and ELPS enabled us to do en bloc resection even for large lesions that could not be treated with EMR or with microscopic surgery. Eight of 49 cases had transient side effects-2 vocal cord palsies, 2 vocal cord edemas with overnight intubation, 3 overnight intubations, and 1 pharyngitis. Six patients died of other diseases, and no metastasis or recurrence of superficial carcinoma was found. Diagnosis and treatment of superficial carcinoma of the hypopharynx may thus improve patient prognosis and QOL.
KW - Carcinoma in situ
KW - Endoscopic mucosal resection (EMR) endoscopic laryngo-pharyngeal surgery (ELPS)
KW - Hypopharyngeal carcinoma
KW - Superficial carcinoma
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U2 - 10.3950/jibiinkoka.109.581
DO - 10.3950/jibiinkoka.109.581
M3 - Article
C2 - 16910578
AN - SCOPUS:33748592308
SN - 0030-6622
VL - 109
SP - 581
EP - 586
JO - Journal of Otolaryngology of Japan
JF - Journal of Otolaryngology of Japan
IS - 7
ER -