Tryptophan Inhibits the [3H]Glutamate Uptake into Xenopus Oocytes Injected with Rat Brain mRNA

Michihisa Tohda; Hisashi Urushihara; Yasuyuki Nomura

doi:10.1254/jjp.59.477

Tryptophan Inhibits the [³H]Glutamate Uptake into Xenopus Oocytes Injected with Rat Brain mRNA

Michihisa Tohda, Hisashi Urushihara, Yasuyuki Nomura

研究成果: Article › 査読

抄録

We characterized the glutamate (Glu) uptake in Xenopus oocytes injected with rat brain mRNA. The Glu uptake into oocytes was higher in mRNA-injected oocytes than in vehicle-injected ones. Na+ omission or addition of tryptophan inhibited the uptake in mRNA-injected oocytes, although it did not affect that in vehicle-injected oocytes. These results suggest that Glu transporters with a tryptophan sensitivity different from that of Glu transporters in native oocytes are expressed after injection of rat brain mRNA.

本文言語	English
ページ（範囲）	477-479
ページ数	3
ジャーナル	The Japanese Journal of Pharmacology
巻	59
号	4
DOI	https://doi.org/10.1254/jjp.59.477
出版ステータス	Published - 1992 1月
外部発表	はい

ASJC Scopus subject areas

薬理学

文献へのアクセス

10.1254/jjp.59.477

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引用スタイル

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