Tubulointerstitial nephritis and uveitis syndrome: A case with an autoimmune reactivity against retinal and renal antigens

Kaori Shimazaki, Guy V. Jirawuthiworavong, Eddy V. Nguyen, Midori Awazu, Ralph D. Levinson, Lynn K. Gordon

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Tubulointerstitial nephritis and uveitis (TINU) generally occurs at young age and has a female preponderance. Renal biopsy reveals interstitial infiltration of inflammatory cells and edema, and the associated intraocular inflammation typically consists of an anterior, bilateral uveitis. The pathogenesis of TINU likely involves both humoral and cellular immunity and is mediated by medications, infectious agents, or other unknown causes. A previous report detected a renal antigen recognized by the serum of a TINU patient. In this report the authors extend these observations to document seroreactivity against a retinal antigen of similar size.

本文言語English
ページ(範囲)51-53
ページ数3
ジャーナルOcular Immunology and Inflammation
16
1-2
DOI
出版ステータスPublished - 2008 1月 1

ASJC Scopus subject areas

  • 免疫アレルギー学
  • 眼科学

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