Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)

Masaru Okamoto, Satoshi Kitajima, Ryuujirou Negishi, Tadateru Maehata, Tsuyoshi Kouro, Shunichi Yamauchi, Hideaki Takahashi, Yoshiki Katakura, Yoshiyuki Watanabe, Ryuichi Abiko, Shinichi Nakaya, Hiroyuki Inaba, Toshifumi Takano, Michihiro Suzuki, Fumio Itoh

研究成果: Article査読

2 被引用数 (Scopus)

抄録

The first evaluated case was a 71-year-old man with melaena. A huge tumor mass was observed in the tale of the pancreas, which we diagnosed as pancreatic carcinoma. Pathological findings confirmed that it was anaplastic pancreas carcinoma (giant cell type). The second case was a 61-year-old woman with upper abdominal pain. Irregular tumors with scattered cysts were observed in the tale of the pancreas, which rapidly increased. Autopsy findings confirmed that it was anaplastic pancreas carcinoma (pleomorphic type). Both cases showed positive for epithelial marker and mesenchymal markers and decrease in stainability by E-cadherin staining, a result which suggested diversity of tumor cells in anaplastic pancreas carcinomas.

本文言語English
ページ(範囲)1656-1665
ページ数10
ジャーナルJapanese Journal of Gastroenterology
105
11
出版ステータスPublished - 2008 12月 1
外部発表はい

ASJC Scopus subject areas

  • 消化器病学

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