TY - JOUR
T1 - Two cohort and three independent anonymous twin projects at the Keio Twin Research Center (KoTReC)
AU - Ando, Juko
AU - Fujisawa, Keiko K.
AU - Shikishima, Chizuru
AU - Hiraishi, Kai
AU - Nozaki, Mari
AU - Yamagata, Shinji
AU - Takahashi, Yusuke
AU - Ozaki, Koken
AU - Suzuki, Kunitake
AU - Deno, Minako
AU - Sasaki, Shoko
AU - Toda, Tatsushi
AU - Kobayashi, Kazuhiro
AU - Sugimoto, Yutaro
AU - Okada, Mitsuhiro
AU - Kijima, Nobuhiko
AU - Ono, Yutaka
AU - Yoshimura, Kimio
AU - Kakihana, Shinichiro
AU - Maekawa, Hiroko
AU - Kamakura, Toshimitsu
AU - Nonaka, Koichi
AU - Kato, Noriko
AU - Ooki, Syuichi
PY - 2013/2
Y1 - 2013/2
N2 - The Keio Twin Research Center has conducted two longitudinal twin cohort projects and has collected three independent and anonymous twin data sets for studies of phenotypes related to psychological, socio-economic, and mental health factors. The Keio Twin Study has examined adolescent and adult cohorts, with a total of over 2,400 pairs of twins and their parents. DNA samples are available for approximately 600 of these twin pairs. The Tokyo Twin Cohort Project has followed a total of 1,600 twin pairs from infancy to early childhood. The large-scale cross-sectional twin study (CROSS) has collected data from over 4,000 twin pairs, from 3 to 26 years of age, and from two high school twin cohorts containing a total of 1,000 pairs of twins. These data sets of anonymous twin studies have mainly targeted academic performance, attitude, and social environment. The present article introduces the research designs and major findings of our center, such as genetic structures of cognitive abilities, personality traits, and academic performances, developmental effects of genes and environment on attitude, socio-cognitive ability and parenting, genes x environment interaction on attitude and conduct problem, and statistical methodological challenges and so on. We discuss the challenges in conducting twin research in Japan.
AB - The Keio Twin Research Center has conducted two longitudinal twin cohort projects and has collected three independent and anonymous twin data sets for studies of phenotypes related to psychological, socio-economic, and mental health factors. The Keio Twin Study has examined adolescent and adult cohorts, with a total of over 2,400 pairs of twins and their parents. DNA samples are available for approximately 600 of these twin pairs. The Tokyo Twin Cohort Project has followed a total of 1,600 twin pairs from infancy to early childhood. The large-scale cross-sectional twin study (CROSS) has collected data from over 4,000 twin pairs, from 3 to 26 years of age, and from two high school twin cohorts containing a total of 1,000 pairs of twins. These data sets of anonymous twin studies have mainly targeted academic performance, attitude, and social environment. The present article introduces the research designs and major findings of our center, such as genetic structures of cognitive abilities, personality traits, and academic performances, developmental effects of genes and environment on attitude, socio-cognitive ability and parenting, genes x environment interaction on attitude and conduct problem, and statistical methodological challenges and so on. We discuss the challenges in conducting twin research in Japan.
KW - adolescence
KW - adulthood
KW - childhood
KW - infancy
KW - longitudinal
KW - twin cohort
UR - http://www.scopus.com/inward/record.url?scp=84873916304&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84873916304&partnerID=8YFLogxK
U2 - 10.1017/thg.2012.131
DO - 10.1017/thg.2012.131
M3 - Article
C2 - 23394192
AN - SCOPUS:84873916304
SN - 1832-4274
VL - 16
SP - 202
EP - 216
JO - Twin Research and Human Genetics
JF - Twin Research and Human Genetics
IS - 1
ER -
