Two new diterpenoids from Leonotis leonurus R. Br.

Yuji Narukawa; Miyuki Komori; Akiko Niimura; Hitomi Noguchi; Fumiyuki Kiuchi

doi:10.1007/s11418-014-0868-2

Two new diterpenoids from Leonotis leonurus R. Br.

Yuji Narukawa, Miyuki Komori, Akiko Niimura, Hitomi Noguchi, Fumiyuki Kiuchi

研究成果: Review article › 査読

6 被引用数 (Scopus)

抄録

Two new diterpenoids, 14α-hydroxy-9α,13α-epoxylabd-5(6)-en-7-on-16,15-olide (1) and 13ξ-hydroxylabd-5(6),8(9)-dien-7-on-16,15-olide (2) along with six known diterpenoids were isolated from the aerial parts of Leonotis leonurus R. Br. These structures were determined on the basis of spectroscopic analyses. Some of the isolated compounds showed weak to moderate estrogen sulfotransferase inhibitory activity.

本文言語	English
ページ（範囲）	130-134
ページ数	5
ジャーナル	Journal of Natural Medicines
巻	69
号	1
DOI	https://doi.org/10.1007/s11418-014-0868-2
出版ステータス	Published - 2015 1月
外部発表	はい

ASJC Scopus subject areas

分子医療

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10.1007/s11418-014-0868-2

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title = "Two new diterpenoids from Leonotis leonurus R. Br.",

abstract = "Two new diterpenoids, 14α-hydroxy-9α,13α-epoxylabd-5(6)-en-7-on-16,15-olide (1) and 13ξ-hydroxylabd-5(6),8(9)-dien-7-on-16,15-olide (2) along with six known diterpenoids were isolated from the aerial parts of Leonotis leonurus R. Br. These structures were determined on the basis of spectroscopic analyses. Some of the isolated compounds showed weak to moderate estrogen sulfotransferase inhibitory activity.",

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AU - Narukawa, Yuji

AU - Komori, Miyuki

AU - Niimura, Akiko

AU - Noguchi, Hitomi

AU - Kiuchi, Fumiyuki

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KW - Estrogen sulfotransferase

KW - Inhibitor

KW - Labiatae

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Two new diterpenoids from Leonotis leonurus R. Br.

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