Two new monoterpene glycosides and trypanocidal terpenoids from Dracocephalum kotschyi

Soodabeh Saeidnia, Ahmad Reza Gohari, Nahoko Uchiyama, Michiho Ito, Gisho Honda, Fumiyuki Kiuchi

研究成果: Article査読

80 被引用数 (Scopus)

抄録

From the whole plant of Dracocephalum kotschyi BOISS., two new monoterpene glycosides (9, 10), together with seven known terpenoids and a phytosterol (1-8), were isolated. Their structures were determined to be limonen-10-al (1), geranial (2), neral (3), β-sitosterol (4), oleanolic acid (5), ursolic acid (6), p-mentha-8-en-1,2-diol (7), colosolic acid (8), limonen-10-ol 10-O-β-D-glucopyranoside (9), and limonen-10-ol 10-O-β-D- glucopyranosyl-(1→2)-β-D-glucopyranoside (10). Compounds 1 (3.1 μM), 2 (3.1 μM), 3 (3.1 μM), 5 (6.2 μM), 6 (6.2 μM), and 8 (6.2 μM) were effective against epimastigotes of Trypanosoma cruzi.

本文言語English
ページ(範囲)1249-1250
ページ数2
ジャーナルChemical and Pharmaceutical Bulletin
52
10
DOI
出版ステータスPublished - 2004 10月
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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