Ultraprecision cutting of single-crystal calcium fluoride for fabricating micro flow cell for protein structure analysis

Ryo Komiya, Tetsunari Kimura, Minoru Kubo, Jiwang Yan

研究成果: Conference contribution

抄録

In infrared spectroscopic analysis of the structures of protein crystals, a micro-flow cell made of single crystal calcium fluoride (CaF2) is needed. In this research, fly cutting of micro grooves on a CaF2 substrate was conducted using a single-crystal diamond tool. The effects of cutting direction, up/down cut, and tool rake angle on ductile-brittle transition of cutting behavior were investigated. Based on the experimental results and analysis, optimal cutting conditions were selected which enabled ductile machining of CaF2. As a result, a 10 μm deep micro-flow cell was successfully fabricated with surface roughness of 2.4 nmRa. The availability of the flow cell was confirmed by visible absorption spectroscopy of protein.

本文言語English
ホスト出版物のタイトルProceedings of the 8th International Conference on Leading Edge Manufacturing in 21st Century, LEM 2015
出版社Japan Society of Mechanical Engineers
出版ステータスPublished - 2015 10月 18
イベント8th International Conference on Leading Edge Manufacturing in 21st Century, LEM 2015 - Kyoto, Japan
継続期間: 2015 10月 182015 10月 22

Other

Other8th International Conference on Leading Edge Manufacturing in 21st Century, LEM 2015
国/地域Japan
CityKyoto
Period15/10/1815/10/22

ASJC Scopus subject areas

  • 産業および生産工学

フィンガープリント

「Ultraprecision cutting of single-crystal calcium fluoride for fabricating micro flow cell for protein structure analysis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル