Ultrasound-triggered controlled release of nanoparticles from hydrogel microbeads by release-promoting particles

Takeshi Kubota, Yuta Kurashina, Hiroaki Onoe

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

We propose an ultrasound-triggered drug delivery system (DDS) with release promoting particles for long-term controlled drug release with low power ultrasound. By using a centrifugal fluidic device, we fabricated calcium alginate hydrogel microbeads containing fluorescent silica nano-particles as a drug model and tungsten micro-particles for promoting release. The silica nano-beads were efficiently released from the microbeads by the ultrasound because the tungsten micro-particles can receive the energy of the applied ultrasound. This ultrasound method will be a key technology of DDS for control of drug release with less burden on the patients.

本文言語English
ホスト出版物のタイトル23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
出版社Chemical and Biological Microsystems Society
ページ756-757
ページ数2
ISBN(電子版)9781733419000
出版ステータスPublished - 2019
イベント23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
継続期間: 2019 10月 272019 10月 31

出版物シリーズ

名前23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
国/地域Switzerland
CityBasel
Period19/10/2719/10/31

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 化学工学(その他)

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