Updates on ossification of posterior longitudinal ligament. Bone metabolism in ossification of posterior longitudinal ligament

Hironari Takaishi, Yuta Shiono, Morio Matsumoto

研究成果: Review article査読

3 被引用数 (Scopus)

抄録

Ossification of the longitudinal ligament in the spine is a disorder of unknown cause characterized by ectopic ossification. In the animal models of spinal hyperostosis, the vertebral ligament is gradually replaced by bony tissue forming an osseous bridge around enthesis, and a high turnover osteopenia occurs after the maturation in the trabecular bone of vertebrae. It has been suggested that the recruited vasculature facilitated the filling of the niche with host-derived haematopoietic cells during the ectopic ossification process. Recent data suggest that regulation of hematopoietic and osteogenic stem/progenitor cell populations may contribute to the formation of an ectopic spinal hyperostosis.

本文言語English
ページ(範囲)1442-1447
ページ数6
ジャーナルClinical calcium
19
10
出版ステータスPublished - 2009 10月

ASJC Scopus subject areas

  • 医学(全般)

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