Urinary catecholamine excretion during gynecological laparoscopy

H. Morisaki, Y. Takino, J. Takahashi, S. Iwanami

研究成果: Article


In 10 patients with ages ranging between 23 and 37 undergoing elective gynecological laparoscopy under pethidine-N2O-pancuronium anesthesia, we measured excretion of norepinephrine (NE) and epinephrine (EN) per 1 mg of urine creatinine in order to evaluate the sympathetic effect of this surgical procedure. Catecholamines were analysed by high-performance liquid chromatography using native fluorescence technique. During laparoscopy, we observed a significant increase in NE and EN excretion (from 73 ± 32 ng/mg·cr to 151 ± 89 ng/mg·Cr and from 24 ± 16 ng/mg·Cr to 39 ± 22 ng/mg·Cr, respectively, mean ± SD). Such increases are considered to be beneficial in maintaining arterial pressure in these cases, where considerable reduction in cardiac output caused by high intraabdominal pressure is expected.

ジャーナルJapanese Journal of Anesthesiology
出版物ステータスPublished - 1986 1 1

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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