Urumamide, a novel chymotrypsin inhibitor with a β-amino acid from a marine cyanobacterium Okeania sp.

Yuki Kanamori, Arihiro Iwasaki, Shinpei Sumimoto, Kiyotake Suenaga

研究成果: Article

6 引用 (Scopus)

抜粋

Urumamide, a novel cyclic depsipeptide that contains a β-amino acid, was isolated from a marine cyanobacterium Okeania sp. Its gross structure was determined by spectroscopic analyses, and the absolute configuration was established based on Marfey's analyses and chiral HPLC analyses of hydrolysis products. Biologically, urumamide inhibited the growth of human cancer cells. In addition, urumamide inhibited chymotrypsin.

元の言語English
ページ(範囲)4213-4216
ページ数4
ジャーナルTetrahedron Letters
57
発行部数37
DOI
出版物ステータスPublished - 2016 9 14

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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