### 抜粋

Purpose: To clarify the effects of respiratory condition on dose calculation for stereotactic radiotherapy of small lung tumors. Methods and materials: Computed tomography (CT) data were obtained for nine tumors (diameter, 2.1-3.6 cm; mean, 2.7 cm) during the stable state, deep expiration, and deep inspiration breath-hold states. Rotational Irradiation with 3 non-coplanar arcs (Rotational Irradiation) and static irradiation with 18 non-coplanar ports (Static Irradiation) using 6-MV photons were evaluated using Fast Fourier Transform (FFT) convolution and Multigrid (MG) superposition algorithms. Dose-volume histograms (DVHs), mean path-length (PL) and mean effective path-length (EPL) were calculated. Results: Although the PL was larger for the inspiration state than for the stable state and the expiration state, the EPL was 0.4-0.5 cm smaller in the inspiration state than in the expiration state (p = 0.01 for Rotational Irradiation; p = 0.03 for Static Irradiation). The isocenter dose obtained by the FFT convolution algorithm was 7-12% higher than that obtained with the MG superposition algorithm. A leftward shift of the DVH obtained by MG superposition was noted for the inspiration state compared with the expiration state. Conclusions: The choice of the proper algorithm is important to accounting for changes in respiration state. Differences in isocenter dose were not large among the respiratory states analyzed. EPL was a little shorter for inspiration than for expiration, although there were larger and reverse trends in path length. A leftward shift of the DVH obtained for the inspiration state when MG superposition was used.

元の言語 | English |
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ページ（範囲） | 204-211 |

ページ数 | 8 |

ジャーナル | Physica Medica |

巻 | 24 |

発行部数 | 4 |

DOI | |

出版物ステータス | Published - 2008 12 1 |

### フィンガープリント

### ASJC Scopus subject areas

- Biophysics
- Radiology Nuclear Medicine and imaging
- Physics and Astronomy(all)

### これを引用

*Physica Medica*,

*24*(4), 204-211. https://doi.org/10.1016/j.ejmp.2008.02.002