Various facets of vertebrate cilia: Motility, signaling, and role in adult neurogenesis

Shihhui Huang, Yuki Hirota, Kazunobu Sawamoto

研究成果: Review article査読

8 被引用数 (Scopus)

抄録

Cilia are microtubule-based cellular organelles that are widely distributed in vertebrate tissues. They were first observed hundreds of years ago. Recent studies indicate that this small organelle plays important roles in numerous physiological phenomena, including tissue morphogenesis, signal transduction, determination of left-right asymmetry during development, and adult neurogenesis. Ciliopathies, syndromes resulting from a genetic disorder of cilial components, frequently have complex effects involving many organ systems, owing to the broad distribution of cilia in the body.

本文言語English
ページ(範囲)324-336
ページ数13
ジャーナルProceedings of the Japan Academy Series B: Physical and Biological Sciences
85
8
DOI
出版ステータスPublished - 2009 10月
外部発表はい

ASJC Scopus subject areas

  • 農業および生物科学(全般)
  • 物理学および天文学(全般)

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