Versatility of thermosensitive particles

H. Kawaguchi, K. Kisara, T. Takahashi, K. Achiha, M. Yasui, K. Fujimoto

研究成果: Article

39 引用 (Scopus)


Poly(N-isopropylacrylamide) (PNIPAM) particles are highly swollen below the transition temperature in water so that they become very soft and hydrophilic, but collapsed above the transition temperature to become hard and hydrophobic. Such changes bring about the discontinuous temperature dependence of adsorbability of protein, activity of immobilized enzyme, cell activating ability of the particles. The transition temperature of PNIPAM was changed by binding something to the chain end and this property was used to control the enzyme activity with temperature. Sudden change in the topology of the particle surface by quick temperature change gave excess stimulus to cells when the change was transmitted straightly to the cells.

ジャーナルMacromolecular Symposia
出版物ステータスPublished - 2000

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

フィンガープリント Versatility of thermosensitive particles' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用