Visible-light-mediated decarboxylative benzoyloxylation of β-hydroxy amino acids and its application to synthesis of functional 1,2-amino alcohol derivatives

Shinsuke Inuki, Keisuke Sato, Yukari Fujimoto

研究成果: Article査読

10 被引用数 (Scopus)

抄録

We have developed a novel method for decarboxylative benzoyloxylation of β-hydroxy amino acids using photoredox catalyst Ru(bpy)3Cl2·6H2O and benzoylperoxide (BzO)2. This strategy was expanded to the synthesis of structurally diverse chiral 1,2-amino alcohols with different aryl or alkyl groups, starting from serine or threonine derivatives.

本文言語English
ページ(範囲)5787-5790
ページ数4
ジャーナルTetrahedron Letters
56
42
DOI
出版ステータスPublished - 2015 10月 14

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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