Xanthones and a benzophenone from the roots of Pentadesma butyracea and their antiproliferative activity

Hippolyte K. Wabo, Haruhisa Kikuchi, Yasuhiro Katou, Pierre Tane, Yoshiteru Oshima

研究成果: Article査読

12 被引用数 (Scopus)

抄録

A new xanthone, 3,4-dihydro-8,10,12-trihydroxy-2,2-dimethylpyrano[2,3-b]xanthen-11(2H)-one or butyraxanthone E (1), along with the known compounds 30-epi-cambogin (2), 1,7-dihydroxyxanthone (3) and 1,5-dihydroxyxanthone (4) were isolated from the roots of Pentadesma butyracea. Their structures were elucidated by spectroscopic means and comparison with published data. Their antiproliferative activities were evaluated against Drosophila S2 cells and two human cancer cell lines, THP-1 (leukemia) and HCT116 (colon cancer). Compounds 1 and 2 showed moderate antiproliferative activity against Drosophila S2 cells and the HCT116 cell line, respectively. Compound 2 was active against Drosophila S2 cells.

本文言語English
ページ(範囲)104-107
ページ数4
ジャーナルPhytochemistry Letters
3
2
DOI
出版ステータスPublished - 2010 6 11
外部発表はい

ASJC Scopus subject areas

  • バイオテクノロジー
  • 生化学
  • 農業および作物学
  • 植物科学

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