TY - JOUR
T1 - Ypaoamides B and C, Linear Lipopeptides from an Okeania sp. Marine Cyanobacterium
AU - Sueyoshi, Kosuke
AU - Yamada, Miki
AU - Yamano, Aki
AU - Ozaki, Kaori
AU - Sumimoto, Shimpei
AU - Iwasaki, Arihiro
AU - Suenaga, Kiyotake
AU - Teruya, Toshiaki
N1 - Publisher Copyright:
© 2018 American Chemical Society and American Society of Pharmacognosy.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2018/4/27
Y1 - 2018/4/27
N2 - Two new pyrrolinone-containing lipopeptides, ypaoamides B (1) and C (2), were isolated from an Okeania sp. marine cyanobacterium collected in Okinawa. Their structures were determined by spectroscopic analysis and Marfey's analysis of acid hydrolysates. Ypaoamides B (1) and C (2) stimulated glucose uptake in cultured rat L6 myotubes. In particular, ypaoamide B (1) showed potent activity and activated AMP-activated protein kinase.
AB - Two new pyrrolinone-containing lipopeptides, ypaoamides B (1) and C (2), were isolated from an Okeania sp. marine cyanobacterium collected in Okinawa. Their structures were determined by spectroscopic analysis and Marfey's analysis of acid hydrolysates. Ypaoamides B (1) and C (2) stimulated glucose uptake in cultured rat L6 myotubes. In particular, ypaoamide B (1) showed potent activity and activated AMP-activated protein kinase.
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U2 - 10.1021/acs.jnatprod.8b00088
DO - 10.1021/acs.jnatprod.8b00088
M3 - Article
C2 - 29667822
AN - SCOPUS:85045977941
SN - 0163-3864
VL - 81
SP - 1103
EP - 1107
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 4
ER -
