Zamamistatin, a significant antibacterial bromotyrosine derivative, from the Okinawan sponge Pseudoceratina purpurea

Noboru Takada, Reiko Watanabe, Kiyotake Suenaga, Kaoru Yamada, Katsuhiro Ueda, Masaki Kita, Daisuke Uemura

研究成果: Article査読

45 被引用数 (Scopus)

抄録

Zamamistatin was isolated from the Okinawan sponge Pseudoceratina purpurea. It was determined to be a novel bromotyrosine derivative by careful analysis of 2D NMR spectra and comparison of its 1H NMR spectrum with those of structurally related compounds. The absolute stereostructure of zamamistatin was determined by the modified Mosher's method. Zamamistatin exhibited significant antibacterial activity against Rhodospirillum salexigens, which has adhering properties.

本文言語English
ページ(範囲)5265-5267
ページ数3
ジャーナルTetrahedron Letters
42
31
DOI
出版ステータスPublished - 2001 7月 30
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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